Effect of a 100mT Static Magnetic Field on Hsp70 mRNA in HL-60 Cells

نویسندگان

  • Michelle Belton
  • Frank S Prato
  • Jeffrey JL Carson
چکیده

Cellular stress response proteins like Hsp70 may be affected by exposure to static magnetic fields (SMF). We examined whether exposure to a 100 mT SMF and GSH-depleting diethymaleate (DEM) would affect the levels of Hsp70 mRNA in HL-60 cells. Cells were exposed to SMF, DEM, a combination of DEM and SMF as well as 42oC. We found that only exposure to 42oC significantly affected the levels of Hsp70 mRNA. Exposure to a 100 mT SMF, DEM, or a combination of SMF and DEM must not affect protein stability thereby altering levels of Hsp70 mRNA.

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تاریخ انتشار 2008